Endocrine Abstracts

Introduction: Octylphenol (OP) is a degradation product of alkylphenol ethoxylates that are widely used to in rubber, pesticides and paints. Bisphenol A (BPA) is an organic compound with two functional phenol groups and used to make polycarbonate plastic and epoxy resins, along with other applications. OP and BPA are known as endocrine disruptors that can induce inappropriate estrogenic action, and may disturb natural calcium metabolism. In the present study, the effects of OP...

Objective: The goal of this study is to evaluate the relationship between levels of adiponectin and vaspin, adiponectin/vaspin (A/V) ratio and metabolic syndrome, degree of adiposity, and insulin resistance (IR), as well as their correlation with metabolic variables.Methods: Two hundred sixty patients with newly diagnosed type 2 diabetes (126 male, 134 female) were enrolled. Patients were grouped based on degree of adiposity, IR assessment (homeostasis m...

Introduction: Activating somatic mutation of the BRAF gene (V600E) has been identified as the most common genetic event in papillary thyroid carcinoma (PTC) with a variable frequency (32–87%) in various races by different methods.In this study, we report the genetic analysis of BRAF mutation in a Korean cohort of 211 PTC by peptide nucleic acid clamp real-time PCR.Methods: PNA clamp real-time PCR was applied for BRAF analysis ...